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. 2014 May 6;9(5):e96756. doi: 10.1371/journal.pone.0096756

Figure 1. Carotid radiotelemetry.

Figure 1

Systolic and diastolic blood pressures (squares and circles, respectively) were measured while mice were housed in their home cage during alternating cycles of darkness (1800 to 0600) and light (0600 to 1800) (A). Compared to wild-type mice (WT, open symbols), heterozygous F508del mice (solid symbols) had lower systolic and diastolic pressures at the dark-to-light transition. Pulse rate (B), locomotor activity (C), and body temperature (D) were not significantly influenced by F508del status. *P<0.05 versus WT; N = 17 WT and 16 F508del mice.