Table 1. Baseline radiotelemetry.
Female | Male | |||
WT | F508del | WT | F508del | |
N | 10 | 8 | 7 | 8 |
Systolic blood pressure (mmHg) | 119±2 | 112±1* | 119±5 | 118±5 |
Diastolic blood pressure (mmHg) | 98±3 | 90±3 | 92±5 | 89±4 |
Pulse rate (bpm) | 560±35 | 582±25 | 605±11 | 599±22 |
Temperature (°C) | 35.2±0.1 | 35.3±0.1 | 34.6±0.2 | 34.4±0.1 |
Arterial waveform-derived systolic blood pressure, diastolic blood pressure and pulse rate were recorded, along with subcutaneous body temperature, every 5 minutes over an 84 h interval while wild-type (WT) and heterozygous F508del mice freely explored their home cage. *P<0.05 versus WT.