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. 2014 May 6;9(5):e96692. doi: 10.1371/journal.pone.0096692

Figure 2. Representative photomicrographs showing TP immunoreactivity in control and MNGIE liver.

Figure 2

Figure 2A demonstrates the lack of TP immunolabeling in a normal liver section in which the primary antibody was omitted (negative control). Figure 2B (low magnification) and 2C (high magnification) illustrate TP immunoreactivity in a normal liver section. In Figure 2C, the arrowhead and circle, (Figure 2C) point to TP immunostained nuclei and cytoplasm of hepatocytes, while the arrow indicates non-hepatocytic cells with features of bile duct elements. Also, note the lack of any TP immunolabeling in a MNGIE liver section (Figure 2D). Calibration bars  = 20 µm and 50 µm in 2C, 2D and 2A, 2B, respectively.