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. 2014 Feb 26;6(3):689–696. doi: 10.4161/mabs.28254

Table 1. Affinity measurements of anti-gD variant binding to mFcRn by surface plasmon resonance.

Variant kon (M−1s−1) koff (s−1) KD (nM)
IgG1
WT
6160 0.0037 601
IgG1
FcRn+
19100 0.0021 108
IgG1
FcRn-
1230 0.1146 93000