Table 1. Clinical features of f-HAM/TSP cases or sporadic cases of HAM/TSP.

	f-HAM/TSP cases (40 cases)	Sporadic cases (124 cases)	p value	p value†
Female ratio (%)	78.8% (7 males : 33 females)	66.4% (31 males : 93 females)	NS
Age	55.6±13.0 (23–79)	61.8±12.5 (15–83)	0.008
Age of onset	41.3±13.9 (14–65)	51.6±15.9 (13–78)	<0.001	0.017
Duration of illness (years)	14.3±11.4 (1–49)	10.2±9.6 (0–45)	0.026	0.017
Initial symptoms
Gait disturbance	50.0%	52.4%	NS
Urinary disturbance	32.5%	26.6%	NS
Sensory disturbance	12.5%	14.5%	NS
Others	5%	6.5%	NS
Rapid disease progression	4 cases (10.0%)	35 cases (28.2%)	0.019	0.069
Motor disability score	4.0±2.0 (0–7)	4.9±1.5 (0–8)	0.043	0.036
Score more than 6	12 cases (30.0%)	38 cases (30.7%)	NS
Time elapsed between onset and wheelchair use in daily life (years)	18.3±12.4 (7–50)	10.0±10.4 (1–45)	0.025	0.020

Data are presented as mean values ± s.d., (range),

^†Adjusted for age and sex.