Table 2. Laboratory findings of familial clusters or sporadic cases of HAM/TSP.
f-HAM/TSP cases (40cases) | Sporadic cases (124 cases) | p value | p value† | |
Anti-HTLV-1 antibodies* | ||||
Titer in Serum | 20,787±31,004, N = 37 | 31,009±36,075, N = 109 | NS | |
Titer in CSF | 2,310±11,741, N = 31 | 672±1,274, N = 111 | NS | |
Cerebrospinal fluid | ||||
Cell number (/mm3) | 3.0±2.5, N = 25 | 5.7±10.0, N = 109 | NS | |
Protein (mg/dl) | 29.9±9.4, N = 22 | 42.5±19.3, N = 109 | <0.001 | 0.007 |
Neopterin (pmol/ml) | 83.2±118.1, N = 18 | 38.3±56.8, N = 35 | NS | |
HTLV-1 proviral loads (Copies/104 PBMCs) | 930±781, N = 32 | 968±1,746, N = 101 | NS |
* Particle Aggregation Method.
Data are presented as mean values ± s.d., N = sample number,
Adjusted for age and sex.