TABLE 4.
mRNA expression in mean RQ ± SEM in the fetal liver from pups exposed to alcohol (8 litters) and saline (7 litters)
| Enzyme | Alcohol (n = 8) | Control (n = 7) | P value |
|---|---|---|---|
| DUOX1 | 1.59 ± 0.26 | 1.09 ± 0.31 | .23 |
| DUOX2 | 0.62 ± 0.26 | 0.42 ± 0.07 | .87 |
| NOX1 | 0.22 ± 0.06 | 0.16 ± 0.04 | .39 |
| NOX2 | 0.33 ± 0.03 | 0.35 ± 0.09 | .86 |
| NOX3 | 0.52 ± 0.27 | 2.11 ± 1.21 | .41 |
| NOX4 | 0.64 ± 0.10 | 1.13 ± 0.32 | .15 |
| NOXA1 | 1.26 ± 0.20 | 0.78 ± 0.17 | .09 |
| NOXO1 | 0.49 ± 0.07 | 0.45 ± 0.07 | .67 |
| RAC1 | 1.11 ± 0.15 | 0.76 ± 0.14 | .12 |
| p22phox | 0.91 ± 0.16 | 0.58 ± 0.10 | .11 |
| p67phox | 0.72 ± 0.13a | 0.29 ± 0.08 | .02 |
RQ, relative quantity.
a
Denotes statistically significant differences (P < .05) between the groups.
Hill. NADPH oxidase and fetal alcohol syndrome. Am J Obstet Gynecol 2014.