Table 2.

Risk of Prostate Cancer According to Categories of Daily Sitting Among 170,481 Men in the NIH-AARP Diet and Health Study, 1996 – 2006

	Cases	Person years	Multivariable adjusted
			HR	95% CI
Total prostate cancer
< 3 h/day	2745	270172	1.00
3 – 4 h/day	4142	424819	0.95	0.90, 1.00
5 – 6 h/day	3859	410382	0.94	0.89, 0.98
7 – 8 h/day	1928	216519	0.93	0.88, 0.99
≥ 9 h/day	1077	124578	0.98	0.91, 1.05
P trend			0.09
By body mass index category (interaction term: p=0.62)
18.5 – 24.9 kg/m2
< 3 h/day	933	86809	1.00
3 – 4 h/day	1363	132031	0.94	0.87, 1.02
5 – 6 h/day	1230	123079	0.94	0.86, 1.02
7 – 8 h/day	583	64628	0.89	0.80, 0.99
≥ 9 h/day	326	35700	0.97	0.85, 1.10
P trend			0.13
25.0 – 29.9 kg/m2
< 3 h/day	1404	137367	1.00
3 – 4 h/day	2081	213025	0.94	0.88, 1.01
5 – 6 h/day	1938	204247	0.94	0.87, 1.00
7 – 8 h/day	957	104720	0.94	0.86, 1.02
≥ 9 h/day	515	57472	0.99	0.89, 1.10
P trend			0.30
≥ 30.0 kg/m2
< 3 h/day	397	45118	1.00
3 – 4 h/day	681	78259	0.98	0.88, 1.01
5 – 6 h/day	681	81684	0.96	0.87, 1.00
7 – 8 h/day	375	46408	1.00	0.86, 1.02
≥ 9 h/day	232	30955	0.99	0.89, 1.10
P trend			0.79
Advanced prostate cancer
< 3 h/day	284	270172	1.00
3 – 4 h/day	408	424819	0.90	0.77, 1.05
5 – 6 h/day	358	410382	0.83	0.71, 0.97
≥ 7 h/day	315	341097	0.91	0.77, 1.08
P trend			0.16
By body mass index category (interaction term: p=0.10)
18.5 – 24.9 kg/m2
< 3 h/day	97	86809	1.00
3 – 4 h/day	134	132031	0.89	0.68, 1.15
5 – 6 h/day	92	123079	0.65	0.49, 0.87
≥ 7 h/day	97	100327	0.86	0.64, 1.14
P trend			0.08
25.0 – 29.9 kg/m2
< 3 h/day	147	137367	1.00
3 – 4 h/day	205	213025	0.89	0.72, 1.10
5 – 6 h/day	177	204247	0.81	0.65, 1.01
≥ 7 h/day	144	162192	0.87	0.69, 1.10
P trend			0.14
≥ 30.0 kg/m2
< 3 h/day	37	45118	1.00
3 – 4 h/day	67	78259	1.03	0.69, 1.55
5 – 6 h/day	86	81684	1.30	0.88, 1.91
≥ 7 h/day	72	77363	1.24	0.82, 1.85
P trend			0.18
Prostate cancer mortality
< 3 h/day	133	270172	1.00
3 – 4 h/day	215	424819	1.01	0.81, 1.25
5 – 6 h/day	168	410382	0.86	0.68, 1.08
≥ 7 h/day	153	341097	1.07	0.84, 1.35
P trend			0.98
By body mass index category (interaction term: p=0.07)
18.5 – 24.9 kg/m2
< 3 h/day	41	86809	1.00
3 – 4 h/day	65	132031	1.01	0.69, 1.50
5 – 6 h/day	39	123079	0.69	0.44, 1.07
≥ 7 h/day	36	100327	0.90	0.57, 1.42
P trend			0.23
25.0 – 29.9 kg/m2
< 3 h/day	70	137367	1.00
3 – 4 h/day	109	213025	0.99	0.74, 1.34
5 – 6 h/day	82	204247	0.83	0.60, 1.15
≥ 7 h/day	74	162192	1.07	0.77, 1.49
P trend			0.91
≥ 30.0 kg/m2
< 3 h/day	22	45118	1.00
3 – 4 h/day	41	78259	1.06	0.63, 1.78
5 – 6 h/day	45	81684	1.16	0.69, 1.93
≥ 7 h/day	43	77363	1.34	0.79, 2.26
P trend			0.18

^aModels are adjusted for age at baseline, age squared, race, marital status, highest level of education, family history of prostate cancer, digital rectal examination in past three years, prostate specific antigen test in past three years, history of diabetes, smoking status, caloric intake, alcohol intake, recreational moderate- to vigorous-intensity physical activity, body mass index at baseline (not models stratified by body mass index).