Table 3.
Cases | Person years | Multivariable adjusted | ||
---|---|---|---|---|
HR | 95% CI | |||
Total prostate cancer | ||||
< 1 h/day | 864 | 94,369 | 1.00 | |
1 – 2 h/day | 4193 | 438771 | 1.01 | 0.94, 1.09 |
3 – 4 h/day | 6224 | 649360 | 1.01 | 0.94, 1.08 |
5 – 6 h/day | 1930 | 205797 | 0.98 | 0.91, 1.07 |
≥ 7 h/day | 540 | 58172 | 1.03 | 0.92, 1.15 |
P trend | 0.53 | |||
By body mass index category (interaction term: p=0.02) | ||||
18.5 – 24.9 kg/m2 | ||||
< 1 h/day | 397 | 41537 | 1.00 | |
1 – 2 h/day | 1541 | 151049 | 1.01 | 0.90, 1.13 |
3 – 4 h/day | 1907 | 184951 | 1.01 | 0.90, 1.13 |
5 – 6 h/day | 482 | 51043 | 0.92 | 0.80, 1.05 |
≥ 7 h/day | 108 | 13667 | 0.82 | 0.66, 1.01 |
P trend | 0.04 | |||
25.0 – 29.9 kg/m2 | ||||
< 1 h/day | 386 | 41823 | 1.00 | |
1 – 2 h/day | 2057 | 216731 | 1.00 | 0.89, 1.11 |
3 – 4 h/day | 3215 | 330940 | 1.00 | 0.90, 1.11 |
5 – 6 h/day | 978 | 101110 | 0.98 | 0.87, 1.11 |
≥ 7 h/day | 259 | 26226 | 1.04 | 0.89, 1.22 |
P trend | 0.98 | |||
≥ 30.0 kg/m2 | ||||
< 1 h/day | 76 | 10581 | 1.00 | |
1 – 2 h/day | 576 | 69501 | 1.13 | 0.89, 1.44 |
3 – 4 h/day | 1078 | 131350 | 1.10 | 0.87, 1.39 |
5 – 6 h/day | 466 | 52932 | 1.16 | 0.91, 1.48 |
≥ 7 h/day | 170 | 18058 | 1.28 | 0.98, 1.69 |
P trend | 0.11 | |||
Advanced prostate cancer | ||||
< 3 h/day | 512 | 533141 | 1.00 | |
3 – 4 h/day | 613 | 649360 | 0.97 | 0.86, 1.10 |
≥ 5 h/day | 240 | 263969 | 0.93 | 0.79, 1.09 |
P trend | 0.49 | |||
By body mass index category (interaction term: p=0.84) | ||||
18.5 – 24.9 kg/m2 | ||||
< 3 h/day | 191 | 192586 | 1.00 | |
3 – 4 h/day | 174 | 184951 | 0.95 | 0.77, 1.18 |
≥ 5 h/day | 55 | 64710 | 0.86 | 0.63, 1.17 |
P trend | 0.44 | |||
25.0 – 29.9 kg/m2 | ||||
< 3 h/day | 252 | 258555 | 1.00 | |
3 – 4 h/day | 309 | 330940 | 0.94 | 0.79, 1.11 |
≥ 5 h/day | 112 | 127336 | 0.88 | 0.70, 1.11 |
P trend | 0.27 | |||
≥ 30.0 kg/m2 | ||||
< 3 h/day | 64 | 80083 | 1.00 | |
3 – 4 h/day | 126 | 131350 | 1.18 | 0.87, 1.59 |
≥ 5 h/day | 72 | 70991 | 1.22 | 0.86, 1.73 |
P trend | 0.22 | |||
Prostate cancer mortality | ||||
< 3 h/day | 205 | 533141 | 1.00 | |
3 – 4 h/day | 320 | 649360 | 1.10 | 0.92, 1.32 |
≥ 5 h/day | 144 | 263969 | 1.07 | 0.85, 1.33 |
P trend | 0.15 | |||
By body mass index category (interaction term: p=0.67) | ||||
18.5 – 24.9 kg/m2 | ||||
< 3 h/day | 71 | 192586 | 1.00 | |
3 – 4 h/day | 82 | 184951 | 1.01 | 0.73, 1.39 |
≥ 5 h/day | 28 | 64710 | 0.83 | 0.53, 1.30 |
P trend | 0.96 | |||
25.0 – 29.9 kg/m2 | ||||
< 3 h/day | 102 | 258555 | 1.00 | |
3 – 4 h/day | 171 | 330940 | 1.17 | 0.91, 1.50 |
≥ 5 h/day | 62 | 127336 | 0.99 | 0.72, 1.38 |
P trend | 0.59 | |||
≥ 30.0 kg/m2 | ||||
< 3 h/day | 31 | 80083 | 1.00 | |
3 – 4 h/day | 66 | 131350 | 1.13 | 0.74, 1.74 |
≥ 5 h/day | 54 | 70991 | 1.52 | 0.97, 2.40 |
P trend | 0.03 |
Models are adjusted for age at baseline, age squared, race, marital status, highest level of education, family history of prostate cancer, digital rectal examination in past three years, prostate specific antigen test in past three years, history of diabetes, smoking status, caloric intake, alcohol intake, recreational moderate- to vigorous-intensity physical activity, body mass index at baseline (not models stratified by body mass index).