Table 1.
Sample Characteristics, Total Sample and by Sex.
| TwinGene | SATSA | |||||
|---|---|---|---|---|---|---|
| Total | Men | Women | Total | Men | Women | |
| n=6130 | n=2675 | n=3287 | n=536 | n=227 | n=309 | |
| Age in years at IPTentry,a mean (SD) | 64.8 (8.1) | 64.8 (8.1) | 65.5 (8.0) | 61.4 (8.1) | 60 (6.6) | 62.0 (8.7) |
| BMI kg/m2 at IPTentry, mean (SD) | 25.9 (3.9) | 25.9 (3.9) | 26.1 (3.4) | 25.7 (3.9) | 25.9 (3.3) | 25.5 (4.3) |
| Older cohort, n (%) | 297 (4.8) | 138 (4.9) | 159 (4.8) | 239 (44.6) | 100 (44.1) | 139 (45.0) |
| Education ≤6 years, n (%) | 1194 (19.5) | 609 (21.4) | 585 (17.8) | 317 (59.1) | 126 (55.5) | 191 (61.8) |
| Genetic risk score, mean (SD) | 28.6 (3.4) | 28.6 (3.4) | 28.6 (3.4) | 28.9 (3.7) | 29.0 (3.6) | 28.9 (3.8) |
| Number of children, mean (SD) | 2.1 (1.0) | 1.9 (1.1) | 2.3 (0.9) | 2.0 (1.4) | 1.9 (1.5) | 2.1 (1.4) |
| Midlife lifestyle factors | ||||||
| No/light exercise, n (%) | 1200 (19.6) | 469 (16.5) | 731 (17.8) | 153 (28.5) | 56 (24.7) | 97 (31.4) |
| Low intake fruit and veg., n (%) | 1589 (25.9) | 1004 (35.5) | 585 (17.8) | 277 (51.7) | 140 (61.7) | 137 (44.3) |
| Never smoked, n (%) | 2744 (44.8) | 1187 (41.8) | 1557 (47.4) | 263 (49.1) | 67 (29.5) | 196 (44.3) |
| Alcohol abstainers, n (%) | 356 (5.8) | 122 (4.3) | 234 (7.1) | 80 (14.9) | 20 (8.8) | 60 (31.4) |
| Diseases (across the study period) | ||||||
| T2DM, n (%) | 561 (9.2) | 342 (12.0) | 219 (6.7) | 92 (17.2) | 41 (18.1) | 51 (16.1) |
| CVD, n (%)b | 3380 (55.1) | 1350 (60.1) | 1470 (50.8) | 209 (39.0) | 104 (45.8) | 105 (34.0) |
| Cancer, n (%) | 434 (7.0) | 234 (8.7) | 200 (6.1) | 60 (11.2) | 32 (14.1) | 28 (9.1) |
| Lung disease, n (%)c | 550 (9.0) | 218 (8.1) | 332 (10.1) | 120 (22.1) | 47 (20.7) | 73 (23.7) |
| All-cause dementia, n (%) | 93 (1.5) | 45 (1.6) | 48 (1.5) | 62 (11.6) | 18 (7.9) | 44 (14.2) |
a
Age at the first in-person testing of BMI
b
Prevalence of one or more CVD (stroke, angina pectoris, heart failure, myocardial infarction, and/or hypertension)
c
Prevalence of one lung disease (asthma, bronchitis, and/or tuberculosis)