Table 3.

Factors Associated with the BMI Trajectory from Age 25 Years to Late Life in Women: Final Model Results

	TwinGene			SATSA
	Estimate	Standard Error	P-value	Estimate	Standard Error	P-Value
Intercept (age 65 years)	23.9314	0.494	<0.001	24.614	0.795	<0.001
Slope A (age 25–65 years)	0.038	0.012	0.001	0.065	0.020	0.001
Slope B (age >65–80 years)	0.018	0.027	0.503	0.052	0.031	0.086
Slope C (age >80 years)	-	-	-	−0.030	0.091	0.746
Demographic
Assessment bias	−0.453	0.046	<0.001	−0.142	0.149	0.339
Cohort	1.756	0.467	<0.001	1.052	0.679	0.123
Cohort*Slope A	0.074	0.011	<0.001	0.056	0.015	<0.001
Cohort*Slope B	−0.030	0.032	0.362	−0.124	0.044	0.005
Cohort*Slope C	-	-	-	-	-	-
Education	−0.014	0.210	0.947	0.216	0.548	0.694
Education*Slope A	0.009	0.005	0.083	0.021	0.014	0.117
Education*Slope B	−0.037	0.023	0.114	0.045	0.035	0.193
Education*Slope C	-	-	-	−0.071	0.125	0.569
Children	0.391	0.077	<0.001	0.097	0.172	0.571
Children*Slope A	0.005	0.001	0.006	0.003	0.004	0.495
Genetic
OGRS	0.128	0.024	<0.001	0.064	0.068	0.346
OGRS*Slope A	0.001	0.0005	0.024	<−0.001	0.002	0.833
Midlife lifestyle factors
Fruit and Veg.*Slope B	0.058	0.029	0.046	0.058	0.037	0.117
Smoking	−0.405	0.156	0.010	−1.499	0.508	0.003
Smoking*Slope A	−0.007	0.004	0.072	−0.025	0.013	0.051
Smoking*Slope B	0.014	0.023	0.534	0.083	0.034	0.015
Alcohol*Slope C	-	-	-	−0.236	0.110	0.031
Diseases (across the study period)
T2DM	3.006	0.299	<0.001	1.913	0.699	0.006
T2DM*Slope A	0.054	0.007	<0.001	0.045	0.017	0.009
T2DM*Slope B	−0.022	0.036	0.542	−0.103	0.040	0.009
CVD	0.659	0.104	<0.001	0.894	0.424	0.035
CVD*Slope A	0.010	0.002	<0.001	0.020	0.011	0.066
Respiratory disease	0.803	0.238	0.001	0.663	0.534	0.215
Respiratory disease*Slope A	0.016	0.238	0.005	−0.002	0.014	0.883
Dementia	−1.540	0.675	0.022	0.348	0.742	0.639
Dementia*Slope A	−0.041	0.019	0.029	−0.007	0.019	0.712
Dementia*Slope B	0.057	0.047	0.225	−0.119	0.043	0.006

Slope A (25 years to <65 years), slope B (≥65 years to <80 years), and slope C (≥80 years)