Table 1. Average Mean Absolute Relative Difference (MARD) values for all four weeks of CGM in mice.
Average Mean Absolute Relative Difference (MARD) values for all four weeks of mice treated with adenoviral vectors bearing VEGF-A or LacZ (Adv-VEGFa or Adv-LacZ), and their untreated (no injection) controls. Error values following the +/− are standard deviations from the average of the individual treatment group’s MARD values. p-values within the boxes represent the statistical significance of the comparisons of the two treatment groups indicated in the axes, calculated by Mann-Whitney U tests, as non-parametric equivalents to student t-tests. Mann-Whitney U tests were conducted because only the Adv-VEGF-A treated group had normally distributed mean MARD values. To test for statistical differences among all three treatment groups at once, a Kruskal-Wallis test was conducted on the MARD values, as a non-parametric equivalent to analysis of variance (ANOVA).
| Total mean MARD data | No Injection: C57BL/6 Average Mean MARD = 23.50 +/− 9.83% (n=26) | Ad-LacZ: C57BL/6 Average Mean MARD = 31.49 +/− 14.50% (n=23) | Ad-VEGFa: C57BL/6 Average Mean MARD =17.44 +/− 5.72% (n=15) |
|---|---|---|---|
| No Injection: C57BL/6 Average Mean MARD = 23.50 +/− 9.83% (n=26) | ---------- | p = 0.021 | p = 0.045 |
| Ad-LacZ: C57BL/6 Average Mean MARD = 31.49 +/− 14.50% (n=23) | ---------- | p = 0.0005 | |
| Ad-VEGFa: C57BL/6 Average Mean MARD = 17.44 +/− 5.72% (n=15) | ---------- |