Table II.

Relative Bias (RB) and Relative Root Mean Square Error (RRMSE) (in Percent) for the Three Levels of Dropout with λ = 2 × 10⁻³ and ω = 1 and for Various Values of the Number of Patients (N = 100, 200, and 400) for SAEM with One and Three Markov Chains, AGQ, and Laplace (LAP) Algorithms

			100				200				400
Parameter	Dropout	N	SAEM 1 chain	SAEM 3 chains	AGQ	LAP	SAEM 1 chain	SAEM 3 chains	AGQ	LAP	SAEM 1 chain	SAEM 3 chains	AGQ	LAP
λ	No	RB	−2.5	18.9	−31.3	−32.2	7.5	1.8	1.6	−31.4	17.5	1.1	1.5	−29.9
		RRMSE	24.3	36.4	33.9	35.2	16.0	20.0	19.9	32.8	20.4	12.7	12.9	30.7
	Low	RB	−11.5	12.8	−0.5	−13.8	5.8	−0.008	1.9	−10.9	18.9	1.8	1.0	−11.3
		RRMSE	26.6	34.6	30.6	35.0	19.3	23.1	23.3	26.0	22.6	16.1	15.6	19.4
	High	RB	−22.9	11.0	−1.2	−19.7	0.4	−1.3	1.5	−17.0	18.5	3.4	1.4	−16.5
		RRMSE	35.0	40.0	39.1	45.9	22.3	27.5	27.1	32.8	23.5	20.6	19.4	25.5
ω	No	RB	−43.0	−22.9	−94.1	−91.3	−52.4	−5.1	−3.6	−94.2	−69.6	−2.1	−2.4	−96.4
		RRMSE	46.2	35.6	96.3	95.5	53.1	22.1	18.5	96.6	70.1	11.6	11.8	97.7
	Low	RB	−30.7	−21.1	−4.4	16.4	−46.2	−3.4	−2.5	15.5	−64.4	−1.4	−1.1	−15.2
		RRMSE	35.6	41.1	35.8	42.6	47.4	27.0	21.3	26.9	65.5	14.6	14.2	20.9
	High	RB	−18.6	−27.1	−9.0	26.1	−40.4	−9.0	−5.9	22.0	−58.8	−3.3	−2.1	22.6
		RRMSE	31.6	49.0	44.8	65.9	42.7	37.3	30.0	39.8	60.7	22.0	21.4	32.0