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. 2014 May;50(100):59–66. doi: 10.1016/j.jaut.2013.11.002

Fig. 5.

Fig. 5

sXBP1 knock down and IL-6 expression following stimulation with SNAPIN. (A) qRT-PCR determining sXBP1 levels in RA SF after siRNA transfection, targeting either XBP1 (siXBP1) or a non-targeting control (siNT) for 48 h in total. Cells were treated with SNAPIN (5 μg/ml) for 24 h. (B) IL-6 levels in culture supernatants measured by ELISA after XBP1 knock down and SNAPIN treatment.