Table 1.
Genotype and allele frequencies of the COMT Val/Met polymorphism in POI patients and a control group
| Population studied | n |
COMT G/A
genotypes |
COMT
Alleles |
Dominant model
|
p | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| GG (%) | GA (%) | AA (%) | p | G (%) | A (%) | p | OR (95% CI) | GG | GA + AA | |||
| POF patients* |
96 |
9 (9.4) |
50 (52.1) |
37 (38.5) |
0.003 |
68 (35.4) |
113 (58.8) |
0.015 |
1.62 (1.10 – 2.39) |
9 |
87 |
0.0008 |
| Control group* | 120 | 33 (27.5) | 47 (39.2) | 40 (33.3) | 113 (47.1) | 127 (52.9) | 33 | 87 | ||||
*Sample groups are in Hardy Weinberg equilibrium.