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Cancer-associated myofibroblasts promote growth of tumor cells. HCT116 (A) and Hke-3 cells (B) were cultured in the absence or the presence of 25, 30, or 50% of condition medium from human cancer-associated fibroblasts. MTT assay and BrdU incorporation were performed as described in the Section “Materials and Methods” at 48 and 72 h of incubation. *p < 0.05, compared to control cells.
