Table 2.
|
|
|
|
Baseline |
End of study |
||||
---|---|---|---|---|---|---|---|---|---|
|
|
|
|
All subjects (N = 15) |
|||||
Withdrawn (N = 5) | Completed (N = 10) | P a | Completed (N = 10) | Difference | P b | ||||
|
Number |
|
|||||||
PS |
1 |
|
|
0 |
2 |
0.79# |
4 |
|
0.15# |
|
2 |
|
|
2 |
4 |
|
4 |
|
|
|
3 |
|
|
3 |
4 |
|
2 |
|
|
|
Mean (SD) |
|
|||||||
6 MWT |
m |
|
257 (160) |
166 (138) |
303 (157) |
0.11 |
282 (171) |
−21.1 (167.7) |
0.70 |
|
% |
|
50.2 (32.2) |
31.0 (24.6) |
59.8 (32.2) |
0.08 |
56.0 (34.5) |
−3.8 (33.3) |
0.73 |
STS |
s |
|
8.0 (4.3) |
7.6 (3.4) |
8.2 (4.8) |
0.80 |
7.0 (3.3) |
−1.2 (3.4) |
0.30 |
S-score | 2.6 (2.4) | 2.2 (2.0) | 2.7 (2.2) | 0.69 | 2.0 (1.8) | −0.7 (2.0) | 0.30 |
Notes: Performance status (PS), six-minute walk distance (6 MWT) in metres (m) and expressed as % predicted (from [21]), Sit-to-stand (STS) test expressed as seconds (s) and as a standard score (S-score) value calculated using age range-specific mean and standard deviations for healthy controls (from [22]): positive scores indicates STS S-scores above the mean. Pa: #Fisher’s exact (for counts) or unpaired t-test (for means) comparing baseline results for patients withdrawn and patients who completed study. Pb : #Fisher’s exact (for counts) or paired t-test (for means) comparing baseline and final test results for patients who completed the study.