Table 2.
Results of univariate analyses of disease-free survival (DFS) and overall survival (OS) time
| Variable | n |
Mean DFS |
P -value |
Mean OS |
P -value |
|---|---|---|---|---|---|
| (months) | (months) | ||||
| CD133 |
|
|
< 0.001 |
|
< 0.001 |
| + |
41 |
42.4 ± 18.2 |
|
37.1 ± 17.7 |
|
| - |
42 |
73.3 ± 16.7 |
|
65.6 ± 15.4 |
|
| KAI1/CD82 |
|
|
< 0.001 |
|
< 0.001 |
| + |
34 |
76.0 ± 19.3 |
|
68.0 ± 17.5 |
|
| - |
49 |
45.5 ± 16.8 |
|
40.1 ± 16.7 |
|
| Gender |
|
|
0.035 |
|
0.067 |
| Male |
75 |
56.4 ± 23.0 |
|
50.0 ± 21.9 |
|
| Female |
8 |
73.1 ± 21.9 |
|
65.6 ± 17.0 |
|
| Age |
|
|
0.854 |
|
0.280 |
| < 60 |
27 |
58.2 ± 21.5 |
|
50.9 ± 19.5 |
|
| ≥ 60 |
56 |
57.9 ± 24.3 |
|
51.8 ± 23.0 |
|
| Location |
|
|
0.004 |
|
0.065 |
| Supraglottic |
51 |
60.3 ± 24.1 |
|
53.9 ± 22.5 |
|
| Glottic |
29 |
56.4 ± 21.8 |
|
49.6 ± 20.5 |
|
| Subglottic |
3 |
35.0 ± 13.7 |
|
29.3 ± 11.2 |
|
| Diameter of tumor |
|
|
0.015 |
|
0.217 |
| < 2.0 cm |
43 |
65.5 ± 19.5 |
|
58.5 ± 18.5 |
|
| ≥ 2.0 cm |
40 |
50.0 ± 24.6 |
|
44.0 ± 22.9 |
|
| Smoking |
|
|
0.122 |
|
0.132 |
| No |
31 |
62.0 ± 26.4 |
|
55.3 ± 22.4 |
|
| Yes |
52 |
55.6 ± 21.2 |
|
49.3 ± 20.1 |
|
| Alcohol |
|
|
0.365 |
|
0.163 |
| No |
33 |
62.4 ± 24.1 |
|
54.9 ± 22.5 |
|
| Yes |
50 |
55.1 ± 22.6 |
|
49.2 ± 21.3 |
|
| Grade of tumor |
|
|
< 0.001 |
|
0.009 |
| Well-differentiated |
30 |
71.7 ± 18.7 |
|
64.4 ± 17.6 |
|
| Moderately-differentiated |
47 |
50.4 ± 22.1 |
|
44.5 ± 20.7 |
|
| Poorly-differentiated |
6 |
49.3 ± 25.3 |
|
42.2 ± 22.8 |
|
| Lymph node metastasis |
|
|
< 0.001 |
|
0.003 |
| No |
49 |
67.6 ± 18.9 |
|
60.5 ± 17.4 |
|
| Yes |
34 |
44.2 ± 22.4 |
|
38.6 ± 21.3 |
|
| pTNM |
|
|
< 0.001 |
|
< 0.001 |
| I and II |
53 |
68.3 ± 19.2 |
|
61.3 ± 17.4 |
|
| III and IV | 30 | 40.0 ± 18.4 | 34.3 ± 18.0 |