Table 4. Association between vitamin D levels, severity of depressive symptoms and use of antidepressants in one, fully adjusted linear regression model (n=355).
| Characteristic |
Calcidiol (25-(OH)D3) |
Calcitriol (1,25-(OH)2D3) |
||||
|---|---|---|---|---|---|---|
| B (s.e.) | β | P | B (s.e.) | β | P | |
| Model 1 (n=355) | ||||||
| Use of a SSRI (1=yes) | −1.73 (2.93) | −0.03 | 0.553 | −7.84 (5.78) | −0.07 | 0.176 |
| Use of a TCA (1=yes) | −3.65 (3.37) | −0.07 | 0.280 | −31.78 (6.64) | −0.27 | <0.001 |
| Use of other antidepressants (1=yes) | −3.84 (2.89) | −0.08 | 0.184 | −2.23 (5.69) | −0.02 | 0.695 |
| Model 2 (n=355) | ||||||
| Use of a SSRI (1=yes) | −1.01 (2.95) | −0.02 | 0.732 | −7.03 (5.82) | −0.07 | 0.228 |
| Use of a TCA (1=yes) | −2.08 (3.49) | −0.04 | 0.553 | −28.13 (6.89) | −0.24 | <0.001 |
| Use of other antidepressants (1=yes) | −3.69 (2.88) | −0.07 | 0.201 | −1.79 (5.68) | −0.02 | 0.753 |
Abbreviations: eGFR, estimated glomerular filtration rate; MMSE, Mini Mental State Examination; SSRI, selective serotonin reuptake inhibitor; TCA, tricyclic antidepressants.
Model 1: Adjusted for age, sex, level of education, smoking status (yes/no), alcohol use (no, moderate, severe), physical activity (low, medium, large), waist circumference, renal function (eGFR), chronic comorbid diseases and global cognitive functioning (MMSE).
Model 2: Similar to model 1, but additionally adjusted for depressive symptom severity and inversus outpatient status.