Figure 5. Genotypic association of GSK 212 and protein signatures.
(A) The four genotypes that are most highly associated with GSK212 (MEK inhibitor) are shown. (B) The CLEA of protein expression (black) and protein phosphorylation (red) is shown for the four selected genotypes. The −log(p-value) of the AUC is represented in different colors. All proteins on the map have a p-value < 0.05 in at least one of the four selected genotypes. Red represents a positive association of protein expression with a cell line class, while green represents a negative association.