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. Author manuscript; available in PMC: 2015 Apr 14.
Published in final edited form as: Cancer Cell. 2014 Apr 3;25(4):415–427. doi: 10.1016/j.ccr.2014.02.008

Figure 5. 3q21q26 mice suffer from three types of leukemia.

Figure 5

(A) Expression profiles of CD34, c-kit, B220, CD3a, Gr-1, Mac-1 and TER-119 in peripheral blood (PB) leukemic cells of 3q21q26 line A (n=5), line B (n=5-6) and line C (n=3) mice as well as mononuclear cells of Tg (−) mice (n=4-5). *, p<0.05; **, p<0.01. (B) Flow cytometric analyses of leukemic cells in 3q21q26 mice. Representative flow cytometric patterns of B-type (left panel), B+GM-type (middle panel) and GM-type (right panel) leukemias are shown. (C) Wright-Giemsa staining of leukemic cells in the peripheral blood of 3q21q26 mice. Scale bar, 10 μm. As a control, mononuclear cells from Tg (−) mice are shown. (D) Frequencies of B-type (white), B+GM-type (gray) and GM-type (black) leukemia developed in the three 3q21q26 mouse lines.

See also Figure S3.