Table 2.
Variablea | Placebo (n=11) | Active (n=10) | P-valueb |
---|---|---|---|
Total pain medication at hour 0 (mg) | 0.0 (0.0, 0.0, 1.7, 6.7) | 0.0 (0.0, 0.0, 0.0, 0.0) | 0.094 |
Total pain medication at hour 2 (mg) | 6.7 (0.0, 2.6, 10.0, 12.0) | 2.0 (0.0, 0.0, 7.2, 20.0) | 0.38 |
Total pain medication at hour 6 (mg) | 10.7 (0.0, 3.3, 14.6, 28.6) | 6.6 (0, 2.2, 9.9, 34.8) | 0.50 |
Total pain medication at hour 12 (mg) | 8.0 (0.0, 5.3, 14.7, 28.0) | 8.8 (0.0, 4.1, 10.0, 20.0) | 0.83 |
Total pain medication at hour 24 (mg) | 12.7 (0.0, 6.6, 37.0, 55.5) | 9.0 (0.0, 3.3, 10.0, 97.3) | 0.20 |
Total 24-hour opiate consumption (mg) | 48.7 (14.0, 24.4, 73.3, 84.6) | 26.6 (11.7, 16.5, 36.3, 151.3) | 0.13 |
Minutes from end of surgery to first PCA morphine request | 50 (16, 36, 90, 166) | 59 (30, 48, 115, 455) | 0.37c |
Notes:
Continuous variables are reported with median (minimum, 25th percentile, 75th percentile, maximum)
P-value given based on Wilcoxon rank sum test
P-value given based on log rank test.
Abbreviation: PCA, patient-controlled morphine analgesia.