Table 2. Population genetic parameters estimated for coding regions of the U.S. CMV isolates using the DnaSP and MEGA programs.
Genomic region | Number of isolates | 1S | 2η | 3π |
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5dS | 6dN | 7ω (dN/dS) |
1a | 24 | 65 | 66 | 0.014 | 0.017 | 0.037±0.006 | 0.005±0.002 | 0.13 |
2a | 27 | 65 | 67 | 0.032 | 0.030 | 0.066±0.012 | 0.020±0.005 | 0.30 |
2b | 28 | 76 | 79 | 0.058 | 0.059 | 0.100±0.021 | 0.045±0.009 | 0.45 |
MP | 26 | 117 | 124 | 0.036 | 0.036 | 0.098±0.012 | 0.010±0.002 | 0.10 |
CP | 26 | 72 | 76 | 0.030 | 0.028 | 0.088±0.012 | 0.006±0.002 | 0.07 |
3′NTR (RNA3) | 28 | 54 | 56 | 0.050 | 0.046 | n/a | n/a | n/a |
Total number of segregating sites.
Total number of mutations.
Nucleotide Diversity, average pairwise nucleotide difference per site.
Mutation rate estimated from S.
The average number of pairwise differences per synonymous site.
The average number of pairwise differences per non-synonymous site.
dS and dN were estimated by Kumar method.