Table 4.

Age-adjusted Rates of Progression and Regression^* of LUTS among Untreated Men and Women (N=3,657), Overall and by Presence of LUTS at Baseline

Baseline LUTS	Progression, %	Regression, %
Total AUASI score
None or Mild	23.3	25.4
Moderate	16.3	49.5
Severe	2.1	93.6
Subdomains
Men
Voiding symptoms†	15.0	48.5
Storage symptoms‡	9.7	39.6
Nocturia¶	19.7	36.9
Women
Voiding symptoms†	13.9	67.2
Storage symptoms‡	21.7	42.1
Nocturia¶	26.9	35.5

^*Defined as 3+ point change in total AUASI between baseline and follow-up study visits. The analysis is of progression included 3,654 individuals eligible for progression, and the analysis of regression included 1,791 individuals eligible for regression based on their baseline AUASI score.

^†Moderate-to-severe voiding symptoms present at baseline, as assessed by AUASI voiding subdomain score >=5 points.

^‡Moderate-to-severe storage symptoms present at baseline, as assessed by AUASI storage subdomain score >=4 points.

^¶Defined as getting up to urinate more than once nightly in the past month fairly often, usually, or almost always, assessed at baseline.