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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Biochem J. 2013 Dec 1;456(2):231–240. doi: 10.1042/BJ20121425

Figure 1. The TRIM25 B30.2 domain structure.

Figure 1

(A) Domain architecture of the full-length TRIM25 molecule highlighting the PRY (blue) and SPRY (red) tandem sequence motifs that comprise the B30.2 domain. (B) Cartoon representation of the three-dimensional structure of the TRIM25 B30.2 domain with the PRY and SPRY regions coloured blue and red respectively. α-Helices and key loops are annotated. (C) Topology diagram of the TRIM25 B30.2 domain with the structural elements coloured according to PRY (blue) and SPRY (red). α-Helices and β-strands are numbered and shown as rounded rectangles and arrows respectively. Loop regions are numbered L1–L13.