Table 1.
Clinical and demographic characteristics of healthy controls, MCI and mild AD subjects at baseline assessment.
| Control | MCI | AD | |
|---|---|---|---|
| # subjects | 229 | 398 | 193 |
| Mean Age | 75.93 ± 5.0 | 74.83 ± 7.48 | 75.33 ± 7.47 |
| Gender (male/female) | 119/110 | 257/141 | 101/91 |
| Smoker/non-smoker | 84/145 | 163/235 | 75/118 |
| Handedness (right/left) | 211/18 | 362/36 | 181/12 |
| Ethnicity (Hispanic/non-Hispanic/unknown) | 2/224/3 | 14/380/4 | 4/187/2 |
| Race (American Indian or Alaskan Native/Asian/African American/White/more than one race) | 0/3/16/210/0 | 1/9/15/372/1/ | 0/2/8/181/2 |
| Mean years of education | 16.04 ± 2.86 | 15.67 ± 3.04 | 14.70 ± 3.1 |
| MMSE | 29.11 ± 0.99 | 27.03 ± 1.77 | 23.32 ± 2.06 |
| CDR global (0–0.5–1) # subjects in each category and mean values | 229–0–0 | 2–396–0 | 0–100–93 |
| 0.0 | 0.49 ± 0.035 | 0.74 ± 0.25 | |
| ADAS-cog | 6.20 ± 2.91 | 11.49 ± 4.42 | 18.36 ± 6.67 |
| APOE (ε2/ε3/ε4) | 38/354/66 | 28/509/259 | 9/214/163 |