Table 4.
Functional gene cluster classifications using the Database for Annotation, Visualization and Integrated Discovery (DAVID) for enrichment scores (ES) > 1.3.
| Gene functional classification | Top 3 associated annotation terms | ||||
|---|---|---|---|---|---|
| Gene cluster | N. of genes | Enrichment score | Annotation category | Annotation term | Enrichment fold |
| 1 | 37 | 1.91 | UP_SEQ_FEATURE | transmembrane region | 3.79 |
| SP_PIR_KEYWORDS | transmembrane | 3.76 | |||
| SP_PIR_KEYWORDS | membrane | 2.99 | |||
| 2 | 8 | 1.78 | SP_PIR_KEYWORDS | Immunoglobulin domain | 35.81 |
| INTERPRO | IPR007110:Immunoglobulin-like | 29.10 | |||
| INTERPRO | IPR003598:Immunoglobulin subtype 2 | 60.95 | |||
| 3 | 4 | 1.70 | UP_SEQ_FEATURE | domain:Sema | 462.41 |
| PIR_SUPERFAMILY | PIRSF005526:semaphorin | 396.21 | |||
| INTERPRO | IPR001627:Semaphorin/CD100 antigen | 403.04 | |||
| 4 | 6 | 1.56 | UP_SEQ_FEATURE | repeat:LRR 10 | 136.13 |
| UP_SEQ_FEATURE | repeat:LRR 9 | 117.98 | |||
| UP_SEQ_FEATURE | repeat:LRR 8 | 106.90 | |||