Dicitrinone B inhibits the proliferation of multiple tumor types. (A) The effects of dicitrinone B on multiple tumor types by WST-1 assay after tumor cells exposure to zero, 10, 20 and 40 μM of dicitrinone B for 48 h. (B) A375 cells were treated with dicitrinone B (zero, 2.5, five, 10, 20 and 40 μM) or 5-fluorouracil (5-Fu) (zero, 25, 50, 100, 200 and 400 μM) for 12, 24 and 48 h. The viability of cells was determined by WST-1 assay. The data are presented as the means ± SD from at least five independent experiments. Significant differences between the treatment and control groups are indicated as * (p < 0.05) or ** (p < 0.01).