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Cytotoxicities of compounds 1–5 against three tumor cell lines in vitro (IC50, μM) a.
| Compound | HepG2 | NCI-H460 | SGC7901 |
|---|---|---|---|
| 1 | 52.1 | >100 | 57.7 |
| 2 | 47.3 | 84.4 | 52.2 |
| 3 | 47.8 | 85.1 | 52.9 |
| 4 | 53.7 | >100 | 57.9 |
| 5 | 54.6 | >100 | 58.1 |
| Adriamycin b | 0.14 | 0.13 | 0.17 |
a IC50 values are means from three independent experiments in which each compound concentration was tested in three replicate wells; b Adriamycin as positive control.
