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IC50 values (µg/mL) and selectivity index (SI) of the diethyl ether extract of J. acutus and of etoposide, on a human tumoral cell line (HepG2) and on murine non-tumoral cells (S17).
| Treatment | IC50 values | SI | |
|---|---|---|---|
| HepG2 | S17 | HepG2 | |
| Extract | 6.2 ± 0.3 * | 34 ± 2.2 | 5.5 |
| Etoposide | 1.9 ± 0.1 | 10 ± 0.01 | 5.4 |
Values represent the mean ± SEM of at least three experiments performed in triplicate (n = 9); * Indicates significant differences (p < 0.01) as compared with S17 cells.
