Table 3.
NMR data for amycolactam (3) in pyridine-d5.
| C/H | δH a | Mult (J in Hz) | δC b | Type |
|---|---|---|---|---|
| 1 | 12.04 | s | NH | |
| 2 | 7.61 | d (2.0) | 124.9 | CH |
| 3 | 112.6 | C | ||
| 4a | 3.93 | dd(15.0, 7.5) | 27.9 | CH2 |
| 4b | 3.78 | dd(15.0, 7.5) | ||
| 5 | 4.26 | m | 57.1 | CH |
| 6 | 4.73 | dd (5.0, 3.5) | 71.4 | CH |
| 6-OH | 6.78 | OH | ||
| 7 | 4.76 | d (5.0) | 74.2 | CH |
| 7-OH | 8.87 | OH | ||
| 8 | 176.8 | C | ||
| 9 | ND c | NH | ||
| 10 | 131.9 | C | ||
| 11 | 5.56 | dd (6.0, 6.0) | 125.1 | CH |
| 12 | 4.02 | m | 32.7 | CH2 |
| 13 | 134.8 | C | ||
| 14 | 7.13 | d (7.0) | 120.1 | CH |
| 15 | 7.29 | dd (8.0, 7.0) | 122.4 | CH |
| 16 | 7.53 | d (8.0) | 110.6 | CH |
| 17 | 138.7 | C | ||
| 18 | 126.4 | C | ||
| 19 | 1.67 | s | 25.8 | CH3 |
| 20 | 1.70 | s | 18.0 | CH3 |
a 600 MHz; b 125 MHz; c Not detected.