Table 1. Top-ranked biological processes represented by IPC-enriched transcripts.
| FlyBase symbol | Gene name | |
|---|---|---|
| Enrichment score: 2.04 | ||
| Annotation cluster 1 | ||
| GO#0032868: response to insulin stimulus | Ilp2 | Insulin-like peptide 2 |
| GO#0032869: cellular response to insulin stimulus | Ilp3 | Insulin-like peptide 3 |
| GO#0043434: response to peptide hormone stimulus | Ilp5 | Insulin-like peptide 5 |
| GO#0008286: insulin-receptor-signaling pathway | chico | Insulin receptor substrate 1 |
| GO#0032870: cellular response to hormone stimulus | Ggamma30A | G-protein gamma 30A |
| GO#0007169: transmembrane receptor protein tyrosine-kinase-signaling pathway | SIFa | IFamide |
| Dh31 | Diuretic hormone 31 | |
| NPF | Neuropeptide F | |
| CCHa2-R | CCHamide-2 receptor | |
| Dh31-R | Diuretic hormone 31 receptor | |
| foxo | Forkhead box, subgroup O | |
| mAChR | Muscarinic acetylcholine receptor 60C | |
| Ms | Dromyosuppressin | |
| Hrs | Hepatocyte growth-factor-regulated tyrosine kinase substrate | |
| Mip | Myoinhibiting peptide precursor | |
| Ras85D | Ras oncogene at 85D | |
| drl | Derailed | |
| fog | Folded gastrulation | |
| Adar | Adenosine deaminase acting on RNA | |
| pix | Pixie | |
| Enrichment score: 1.67 | ||
| Annotation cluster 2 | ||
| GO#0006006: glucose metabolic process | Pfk | Phosphofructokinase |
| GO#0019318: hexose metabolic process | Mdh2 | Malate dehydrogenase 2 |
| GO#0005996: monosaccharide metabolic process | Ald | Aldolase |
| GO#0006096: glycolysis | Idh | Isocitrate dehydrogenase |
| GO#0006007: glucose catabolic process | Mdh1 | Malate dehydrogenase |
| GO#0019320: hexose catabolic process | CG9467 | Dmel_CG9467 |
| CG8460 | Dmel_CG8460 | |
| Vha26 | Vacuolar H[+]-ATPase 26kD E subunit | |
| Vha55 | Vacuolar H[+]-ATPase 55kD B subunit | |
| foxo | Forkhead box, subgroup O | |
| Enrichment score: 1.54 | ||
| Annotation cluster 3 | ||
| GO#0060538: skeletal muscle organ development | unc-104 | Kinesin-like protein unc-104 |
| GO#0048747: muscle fiber development | Frq1 | Frequenin 1 |
| GO#0007519: skeletal muscle tissue development | Gs2 | Glutamine synthetase 2 |
| GO#0014706: striated muscle tissue development | Vap-33-1 | Dmel_CG5014 |
| GO#0060537: muscle tissue development | drl | Derailed |
| GO#0050808: synapse organization | foxo | Forkhead box, subgroup O |
| Mef2 | Myocyte-enhancing factor 2 | |
Each annotation cluster represents GO terms with similar biological functions determined by DAVID. Biological functional clusters were ranked based on the enrichment score. The top six GO terms that have the lowest P-values (most enriched) within each cluster are shown. All genes involved in each cluster are shown. Full list of the GO terms of each cluster is in Table S5.