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. 2014 Mar 20;197(1):77–89. doi: 10.1534/genetics.113.161091

Table 2. Mutation frequencies in adult worms and germline carriers in adult worms.

Gene/TALEN pair(s) No. of worms raised No. of mature adults screened No. of mutation-positive adults Mutation frequency (% mutation-positive adults) % mutant genome copiesa No. of germline carriers (carrier ID)
erEx2_L/R + erEx3_L2/R2 60 60 6 5% (3/60 indels); 3% (2/60: large deletion); 1% (1/60: inversion) 10–23% (indels) 6–12% (large deletions) <1% (inversion) 2 (er+32; er+59: large deletions)
erEx3_L2/R2 6 6 0 0% NA NA
l-cryEx2_L/R + l-cryEx3_L/R >80 62 27 43% (27/60: indels) 9% (6/60: large deletions and indels) 5–∼100% (indels) Not measured 1 (l-cry+36: indels and large deletion)
vtnEx2_L/R 13 13 3 20% (indels) Not measured 0

Calculated from intensity of uncut or deletion band. Indicates individual mutation rate. See also Figure S5C.