Table 1.

Discrepancies between registered and published primary outcomes.

Registered and published primary outcomes	BMJ (39)	JAMA (36)
No discrepancy between registered and published primary outcome	21 (53%)	29 (81%)
No primary outcome registered	2 (5%)	1 (3%)
Change in timing of the assessment of the primary outcome	4 (10%)	1 (3%)
New primary outcome introduced in the paper	7 (18%)	3 (8%)
Registered primary outcome not reported in the paper	2 (5%)	0
Registered primary endpoint reported as secondary outcome in the paper	1 (3%)	1 (3%)
Registered primary endpoint reported in a previous publication	1 (3%)	0
Registered secondary outcome reported as a primary outcome in the paper	1 (3%)	0
Change in study population	0	1 (3%)