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. Author manuscript; available in PMC: 2014 May 15.
Published in final edited form as: Neuroimage. 2013 Jan 28;72:33–40. doi: 10.1016/j.neuroimage.2013.01.039

Figure 2.

Figure 2

Simulation of the relationship between the measured signal and true CBVv for the new method (Eq. [11]). (a) The effect caused by the distribution of vessel scales was examined by altering the fraction of the total CBV occupied by venous vessels (Ωv), whilst keeping the combined capillary and venous fraction constant. (b) Hyperoxia has been shown to cause a reduction in CBF (ΔCBF), hence the effect of a 5% flow reduction was examined. (c) It has also been suggested that hyperoxia may alter resting CMRO2. CMRO2 changes of ±10% (ΔCMRO2) were considered.