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. 2011 Jul 4;8(5):371–379. doi: 10.1038/cmi.2011.19

Table 2. AP-1-dependent miRNAs.

miRNA Stimulus Alteration Transcription factors Cell lines Reference
miR-21 PMA; ectopic expression of HER2/neu Up c-Fos; c-Jun Side population cells from various cancer cell lines; human breast cancer cell line; human promyelocytic leukemia cell line 40, 41, 95
miR-155 B-cell receptor cross-linking Up FosB and JunB Human lymphoma cell 43
miR-146b The two PDGF ligands AA and BB Up c-fos Human glioblastoma and ovarian cancer cells 42
miR-99a The tyrosine kinase c-Src Down ND Human c-Src-transformed cells 44

Abbreviations: ND, not determined; PDGF, platelet-derived growth factor; PMA, phorbol 12-myristate 13-acetate.