Skip to main content
. 2010 Sep 13;31(10):1303–1311. doi: 10.1038/aps.2010.157

Figure 1.

Figure 1

Effects of Cl− channel blockers on volume-activated Cl− currents in rat mesenteric arterial smooth muscle cells. (A) Sample traces of whole-cell currents were studied at different voltages generated by stepwise depolarization, in steps of 10 mV, from −100 to +100 mV, with a holding potential of −50 mV. Volume-activated Cl− currents were activated by exposing the cells to a hypotonic extracellular solution in the absence (control) or presence of 100 μmol/L DIDS or 50 μmol/L NPPB (n=6). (B) Current-voltage relationship for steady state current measured at different membrane potentials. Data were expressed as means±SEM (n=6).