Table 3. Genotype distribution and allele frequency of all investigated single nucleotide polymorphisms (SNPs) in thoracic aortic dissection (TAD) patients and control subjects.
| dbSNP ID | Genotype (%) |
MAF | Genotype (%) |
MAF | P# | P↑ | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Patients | Patients | |||||||||
| rs819146 | GG (3.9) | GT (29.8) | TT (66.3) | G=0.188 | GG (5.0) | GT (35.0) | TT (60.0) | G=0.225 | 0.202 | 0.198 |
| rs8003379 | CC (0.0) | CA (0.4) | AA (99.6) | C= 0.002 | CC (0.0) | CA (1.1) | AA (98.9) | C=0.006 | 0.486 | NA |
| rs2853523 | AA (4.4) | AC (32.0) | CC (63.6) | A=0.202 | AA (3.9) | AC (31.8) | CC (64.3) | A=0.198 | 0.914 | 0.973 |
| rs326118 | GG (3.4) | GT (24.3) | TT (72.3) | G=0.155 | GG (3.9) | GT (25.0) | TT (71.1) | G=0.164 | 0.746 | 0.791 |
| rs3788205 | TT (6.8) | TC (29.1) | CC (64.1) | T=0.214 | TT (4.4) | TC (36.7) | CC (58.9) | T=0.223 | 0.220 | 0.296 |
| rs10757278 | GG (18.9) | GA (50.8) | AA (30.3) | G=0.444 | GG (27.4) | GA (48.0) | AA (24.6) | G=0.514 | 0.054 | 0.220 |
#
according to the allelic test
↑
according to the dominant model; MAF, minor allelic frequency (based on whole sample)
NA, not applicable