Table 2. The significantly associated genes with dynamic regulation pattern in signaling pathways during aging.
| Genes | Related pathways | p1 (L4 to D6) | p2 (D6 to D15) |
|---|---|---|---|
| ced-2 | MAPK signaling pathway | 1.70E-02 | 3.62E-04 |
| lin-45 | MAPK signaling pathway mTOR signaling pathway ErbB signaling pathway | 1.34E-03 | 1.87E-03 |
| ZK856.8 | MAPK signaling pathway | 1.03E-03 | 7.11E-03 |
| F59D6.7 | MAPK signaling pathway | 1.41E-02 | 2.17E-02 |
| pdk-1 | mTOR signaling pathway | 4.58E-04 | 1.19E-02 |
| cyd-1 | Wnt signaling pathway | 4.50E-03 | 1.58E-03 |
| sma-4 | Wnt signaling pathway TGF-beta signaling pathway | 9.60E-03 | 5.51E-03 |
| skr-7 | Wnt signaling pathway TGF-beta signaling pathway | 3.76E-06 | 2.05E-02 |
| skr-8 | TGF-beta signaling pathway | 3.12E-05 | 4.59E-02 |
| skr-9 | Wnt signaling pathway TGF-beta signaling pathway | 1.03E-04 | 3.57E-02 |
| skr-13 | Wnt signaling pathway TGF-beta signaling pathway | 1.34E-05 | 2.27E-03 |
| skr-14 | Wnt signaling pathway TGF-beta signaling pathway | 5.99E-05 | 6.63E-03 |