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Funnel plot for publication bias showing the relationship between the effect size of individual studies and the precision of the study estimate for the PTEN/PI3K/Akt signaling pathway. (A): Hazard ratio for unadjusted overall survival. (B): Hazard ratio for adjusted overall survival. (C): Hazard ratio for unadjusted progression-free survival.
Abbreviations: PI3K, phosphoinositide 3-kinase; PTEN, phosphatase and tensin homolog deleted on chromosome 10.
