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. 2014 May 7;9(5):e91376. doi: 10.1371/journal.pone.0091376

Table 3. Potential upstream regulators of SCAP/SREBP pathway (ranked by P-value).

E17.5 Only		E17.5 Insig^Δ/Δ		E17.5 Scap^Δ/Δ		E18.5 Scap^Δ/Δ		PN1 Scap^Δ/Δ
Gene	P value	Gene	P value	Gene	P value	Gene	P value	Gene	P value
FOXO3	0.000599	SREBF2	2.44E-09	WT1	5.33E-06	SREBF2	3.26E-06	SREBF2	1.02E-12
IRF7	0.000997	TRIM24	2.07E-08	SPDEF	7.2E-06	FOXO4	4.17E-06	SREBF1	3.51E-10
E2F4	0.00373	SIRT2	5.33E-06	PROX1	2.32E-05	SREBF1	1.85E-05	SIRT2	3.59E-10
CTNNB1	0.00663	TP53	1.76E-05	KLF2	7.18E-05	NR1H3	0.000022	FOXO4	4.6E-07
POU4F1	0.00881	PPARA	0.000106	HHEX	9.65E-05	SIRT2	3.64E-05	PPARA	2.49E-05
GLI1	0.00989	WT1	0.000106	NFE2L2	0.000435	NR1H2	0.000452	NR1H2	7.24E-05
GATA3	0.0231	STAT3	0.00018	NOTCH1	0.000699	STAT6	0.000464	PPARGC1B	0.000173
SPDEF	7.2E-06	Smad2/3/4	0.000599	HTT	0.000829	PPARGC1B	0.00071	NR1H3	0.000189
		TOB1	0.000724	NFkB	0.000905	PPARA	0.00305	PPARG	0.00088
		SREBF1	0.000742	IRF7	0.000997	ETS1	0.00485	ESRRA	0.0017