Figure 3. Intracoronary infusion of CSCs alleviates LV dysfunction induced by MI.

At 35 days, hemodynamic measurements were performed using a Millar catheter in both vehicle- (n = 9) and CSC-treated mice (n = 7). A and B, Representative pressure-volume (P-V) loops from a vehicle-treated and a CSC-treated mouse recorded at baseline and during preload manipulation by a brief occlusion of the inferior vena cava. C, D, and E, Quantitative analysis of hemodynamic variables including LV end-diastolic pressure, ejection fraction and end-systolic elastance (Ees). Values are means±SEM. *, p<0.05 vs. vehicle group.