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. 2014 May 7;9(5):e96421. doi: 10.1371/journal.pone.0096421

Figure 7. Decreased IL-10 mRNA transcripts in lung CD4+ T cells correlate with worsening emphysema.

Figure 7

Lung CD4+ T cells were isolated for analysis of IL-10 mRNA by real-time RT-PCR. (A) mRNA transcripts presented in the Group A and Group B subject groups defined in Figure 4. Symbols, which represent individual subjects, are as described in the Legend to Figure 6; lines represent the mean ± SEM. The Mann Whitney t-test was used to determine significant differences between groups; N.S., not significant. (B) Relationship of IL-10 mRNA transcripts in lung CD4+ T cells, expressed as arbitrary units (vertical axis), to percent emphysema (−950 HU threshold) (horizontal axis) (n = 17). Spearman non-parametric analysis was used to calculate rS and p values.