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. 2014 May 7;9(5):e96787. doi: 10.1371/journal.pone.0096787

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© 2014 Smutek et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The bar graphs show the mean numbers of licks on the bottles with 12% alcohol adulterated with increasing concentrations of quinine of a cohort of 10 male mice (see Table S1 for a summary of the experiment). Each bar corresponds to a single 24-h interval, and only intervals with access to alcohol are shown. Analysis of variance indicated that the means were significantly different (F_3,56 = 26.54, p<0.001; Tukey's HSD post hoc P<0.01 ** and P<0.001 ***). There was no significant difference between mean numbers of licks on the alcohol bottles before adulteration and after adulteration with 0.01% quinine.