Figure 5. Upper panels are confocal microscopic images showing transgenic expression of DsRed reporter gene in Baboon ID#18175 pancreas. Insulin cells are virtually absent. DsRed colocalizes with glucagon in α-cell clusters/islets. Scale bar is 50 µm. Lower panel is RT-PCR for DsRed cDNA in Baboon ID#18175: (A), pancreatic head; (B), pancreatic middle; (C), pancreatic tail; (D) spleen; (E) liver; (F) heart; (G) skeletal muscle.