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Schematic representation of the secondary structure of the citrate carrier, which consists of 6 transmembrane helices (H1–H6), connected by 3 loops on the matrix side (M1–M3) and 2 loops on the intermembrane space (C1, C2). Matrix loops contain short amphipatic helices (h1–2, h3–4, and h5–6). CS, carrier signature.
