Skip to main content
. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Mol Cancer Ther. 2014 Jan 16;13(5):1194–1205. doi: 10.1158/1535-7163.MCT-13-0341

Figure 4. JQ1 is not a direct JAK kinase inhibitor.

Figure 4

(A) The indicated cell line was treated with JQ1 (0.5 μM) and harvested at the indicated time points, after which immunoblots were performed for phosphorylated and total STAT5. (B) The effect of JQ1 (0.5 μM) on the activity of selected tyrosine kinases was analyzed using SelectScreen Kinase Profiling (Invitrogen). Jak inhibitor 1 (0.5 μM) was used as positive control for inhibition of Jak family kinases.