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. Author manuscript; available in PMC: 2014 May 30.
Published in final edited form as: Stat Med. 2013 Dec 13;33(12):2004–2016. doi: 10.1002/sim.6073

Table 2.

Empirical size and power for the single-stage and minimax and optimal two-stage designs listed in Table 1

Single-Stage Minimax Optimal



r Δ Size Power Size Power Size Power
(α, 1 − β) = (0.05, 0.9)
30 1.4 0.043 0.881 0.044 0.876 0.046 0.874
1.5 0.043 0.878 0.043 0.879 0.045 0.883
1.6 0.039 0.880 0.041 0.889 0.043 0.882
1.7 0.042 0.890 0.041 0.895 0.043 0.889

(α, 1 − β) = (0.1, 0.9)
1.4 0.091 0.878 0.091 0.882 0.091 0.880
1.5 0.092 0.880 0.091 0.881 0.091 0.881
1.6 0.093 0.893 0.091 0.887 0.087 0.879
1.7 0.091 0.890 0.087 0.886 0.091 0.890

(α, 1 − β) = (0.05, 0.85)
1.4 0.044 0.827 0.044 0.834 0.044 0.827
1.5 0.045 0.840 0.049 0.825 0.043 0.832
1.6 0.043 0.841 0.043 0.838 0.043 0.835
1.7 0.043 0.838 0.047 0.842 0.043 0.839

(α, 1 − β) = (0.05, 0.9)
60 1.4 0.044 0.889 0.044 0.883 0.047 0.889
1.5 0.043 0.890 0.045 0.888 0.043 0.887
1.6 0.043 0.892 0.041 0.891 0.046 0.896
1.7 0.043 0.900 0.045 0.899 0.043 0.891

(α, 1 − β) = (0.1, 0.9)
1.4 0.092 0.894 0.094 0.890 0.096 0.888
1.5 0.094 0.890 0.094 0.894 0.098 0.886
1.6 0.090 0.895 0.094 0.888 0.096 0.892
1.7 0.092 0.901 0.092 0.896 0.093 0.891

(α, 1 − β) = (0.05, 0.85)
1.4 0.045 0.838 0.046 0.847 0.045 0.844
1.5 0.045 0.844 0.046 0.843 0.045 0.846
1.6 0.041 0.851 0.043 0.845 0.043 0.846
1.7 0.041 0.849 0.040 0.843 0.045 0.847