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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Ann Neurol. 2014 Mar 13;75(4):508–524. doi: 10.1002/ana.24100

Figure 5.

Figure 5

Reduced growth of the ischemic CN was not associated with enhanced delayed cell death or proliferation at 4 weeks after HI. (A) Typical low density of apoptotic cells (white arrow; inset shows higher power detail), double-labeled with Hoechst (blue) and anti-caspase 3 (AC3; red) antibody. (B) There were no significant differences in the magnitude of apoptosis between the control and HI groups defined by quantification of AC3 labeling in the entire CPu; p = 0.20. (C) Typical low density of proliferating cells (white arrows; higher power detail in the inset), double-labeled with Hoechst (blue) and anti-Ki67 antibody (see inset). (D) No differences in cell proliferation were detected between the two groups, as defined by quantification of Ki67 in the entire CPu; p = 0.45. Scale bars in A and C = 100 μm; insets = 15 μm.