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Delta-like ligand 4 (Dll4) immunohistochemical staining of human cutaneous foreign body granulomatous reactions and sarcoidosis. Dll4 demonstrated specific cytoplasmic and variable nuclear staining within mono- and multinucleated histiocytes in both FBGR (A, 100× magnification and B, 600× magnification) and epithelioid histiocytes in cutaneous sarcoidosis (C, 100× magnification and D, 600× magnification). Dll4 staining of dermal endothelial cells (E, 400× magnification).
